The subject of belimumab may improve skin in scleroderma mdedge rheumatology encompasses a wide range of important elements. Belimumab may improve skin in scleroderma - MDedge. MAUI, HAWAII – Belimumab shows promise as a novel biologic treatment for skin involvement in early diffuse cutaneous systemic sclerosis, Janet E. Pope, MD, said at the 2020 Rheumatology Winter Clinical Symposium.
Belimumab for the Treatment of Early Diffuse Systemic Sclerosis. Moreover, to assess the safety and efficacy of treatment with belimumab in patients with early diffuse cutaneous systemic sclerosis (dcSSc) treated with background mycophenolate mofetil (MMF). Researchers Test Belimumab in Scleroderma - The Rheumatologist. A human monoclonal antibody that inhibits B cell activating factor, belimumab (Benlysta)—an FDA-approved treatment for lupus—was chosen as a candidate for the pilot study because of the important role B cells play in the pathogenesis of systemic sclerosis. Belimumab and Rituximab Combination Therapy for the Treatment of ....
It is hypothesized that that Rituximab and Belimumab combination therapy with Mycophenolate Mofetil background therapy will improve fibrosis in SSc skin when compared to treatment with placebo and Mycophenolate Mofetil in a group of patients with early dcSSc. The purpose of this project is to determine the safety, efficacy, and tolerability of belimumab (Benlysta) in combination with mycophenalate mofetil (MMF, Cellcept ®) in the treatment of early diffuse cutaneous systemic sclerosis (diagnosis <3 years). A Phase 2/3, randomized, double-blind, placebo-controlled, parallel .... The study drug is being tested to determine if it will work and be safe for the treatment of ILD for patients with diffuse scleroderma and if it helps with other aspects of the disease associated with scleroderma such as skin thickening.
Belimumab in Scleroderma, Systemic and Systemic Sclerosis ... This study investigates the efficacy and safety of belimumab compared to placebo, in addition to standard therapy, for the treatment of participants with systemic sclerosis associated interstitial lung disease (SSc-ILD). Objective: To assess the safety and efficacy of treatment with belimumab in patients with early diffuse cutaneous systemic sclerosis (dcSSc) treated with background mycophenolate mofetil (MMF). Belimumab may improve skin disease, pilot study finds..
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