In recent times, molecular subtype specific biomarkers improve prediction of prognosis has become increasingly relevant in various contexts. Molecular-Subtype-Specific Biomarkers Improve Prediction of Prognosis .... The results illustrate that our extended subtyping framework, combining subtyping and subtype-specific biomarkers, could contribute to improved patient prognostication and may form a strong basis for future studies. Improving molecular subtypes and prognosis of pancreatic cancer through .... Our study redefined pancreatic cancer’s molecular subtype and prognosis model by comprehensively analysing patients’ multi-group data.
Using ten clustering algorithms, we developed two subtypes of PAC molecules with different features. Molecular subtyping is employed to reduce the major inter-tumor molecular diversity of CRC and allows patient prognosis to be more accurately predicted within each subtype by application of subtype-specific prognostic biomarker panels. Biomarkers in Cancer Detection, Diagnosis, and Prognosis. These algorithms can identify genomic alterations, mutations, and biomarkers associated with specific cancer types, helping in diagnosis, prognosis, and personalized treatment selection.
Identification and validation of stemness-related gene signatures to .... Identifying novel biomarkers will enable more precise predictions of prognosis and immune infiltration. However, despite these insights, there remains a lack of comprehensive understanding regarding the specific molecular features and prognostic significance of high-stemness cell clusters within the osteosarcoma tumor microenvironment. In this study, we aimed to identify Consensus Molecular Subtype (CMS) specific prognostic genes of colon cancer, focusing on anti-tumor immune- response associated CMS1, through a...
Molecular features of the cancer cell intersubtypes identified within each of the three CC archetypes (in S1G). Two closely related intersubtypes (denoted Type 1a and 1b) were discovered within the secretory archetype for the SYSCOL cohort and within the Serrated archetype for the GSE39582 dataset. Data Augmentation to Improve Molecular Subtype Prognosis Prediction in .... To the best of our knowledge, this paper is the first work that proposes the application of DA to improve the predictive performance of prognosis associated with molecular subtypes of breast cancer using genomic data. Molecular biomarkers, network biomarkers, and dynamic network ....
In summary, we have comprehensively reviewed recent advances and applications of molecular biomarkers, network biomarkers, and dynamic network biomarkers in diagnosis, prediction, and therapy for rare diseases. This perspective suggests that, molecular subtypes based on DNA sensors predict prognosis and tumor .... The relationship between the DNA sensors and the prognosis of HCC patients was explored. In addition, the DNA sensors were employed to classify HCC into multiple molecular subtypes, and the immunophenotypic characteristics across the subtypes were comparatively analyzed.
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